Methylene blue is a chemical compound widely known for its antiseptic, antifungal and bactericidal properties. Its use in the treatment of mouth sores, ulcers and oral mucositis has been studied in order to improve its effectiveness.
In this article, we will explore in depth the benefits of methylene blue for treating oral lesions, its mechanism of action, and recent innovations describing its advanced use in the treatment of canker sores, ulcers, and oral mucositis .
Benefits of Methylene Blue for Mouth Sores
🔹 Antiseptic and Antifungal Properties
Kills bacteria and fungi, preventing infections in open wounds inside the mouth.
🔹 Accelerates Healing
It promotes the regeneration of damaged tissues, reducing the healing time of canker sores and mouth ulcers.
🔹 Pain and Inflammation Relief
It has an analgesic effect that relieves discomfort caused by mouth sores.
🔹 Easy to Apply and Economical
🔹 Application in Patients with Oral Mucositis
It is especially useful in patients undergoing chemotherapy or radiotherapy , as it helps relieve oral mucositis and prevent secondary infections.
Methylene Blue for the Treatment of Oral Lesions
Patent WO2018126107A1 presents an innovative approach to the use of methylene blue for the treatment of ulcers, canker sores, stomatitis and oral mucositis . Its findings support the efficacy of this compound in the treatment of oral lesions through advanced formulations that maximize their effectiveness and safety.
Composition and Formulation
- The active ingredient is methylene blue , formulated in various presentations: solutions, gels, pastes, films and dissolvable tablets .
- Its purpose is to ensure direct contact with the injury , promoting healing and relieving pain.
Mechanism of Action
- Antiseptic effect: Kills microorganisms and reduces the risk of infections.
- Anti-inflammatory property: Reduces inflammation of damaged tissues.
- Photodynamic action: When exposed to light, it generates free radicals that eliminate microorganisms.
Application Forms
- Solutions or gels: They are applied directly to the lesion with a swab.
- Adhesive films: They adhere to the oral mucosa, providing a prolonged effect .
- Dissolvable tablets: They break down slowly in the mouth, releasing methylene blue in a controlled manner.
Key Benefits
✔ Immediate pain reduction.
✔ Acceleration of healing.
✔ Lower risk of infection.
✔ Easy application at home or in clinical settings.
Clinical Applications
- Oral mucositis in patients with cancer.
- Recurrent canker sores and mouth ulcers.
- Oral lesions in immunosuppressed individuals.
- Preventive use in people prone to developing mouth sores.
How to Use Methylene Blue for Mouth Sores
1️⃣ Wash your hands before applying the product.
2️⃣ Use a cotton swab to apply the methylene blue directly to the sore.
3️⃣ Do not rinse your mouth immediately after application so that the product can take effect.
4️⃣ Repeat the process 2-3 times a day until the lesion disappears.
⚠ Caution: Do not over apply.
Side Effects and Precautions
Although safe for topical use, methylene blue can cause:
❌ Irritation in sensitive people.
❌ Temporary stains on the tongue and teeth.
❌ Allergic reactions in some cases.
❌ Interactions with certain medications.
💡 See a doctor if sores do not improve within 7-10 days.
Natural Alternatives for Mouth Sores
If you prefer other options, you can try:
✔ Rinse with water and salt.
✔ Aloe vera gel.
✔ Sodium bicarbonate (anti-inflammatory effect).
✔ Honey (antimicrobial and soothing properties).
Conclusion
Methylene blue is a highly effective option for treating mouth sores, mouth ulcers and oral mucositis , thanks to its antiseptic, healing and anti-inflammatory properties. Patent WO2018126107A1 supports its advanced use in formulations designed to maximize its efficacy and safety, offering an innovative treatment for patients with oral lesions.
